A lady with grey hair and sunglasses holding a cocktail
December 6, 2022

What Took So Long? – How Tech Has Finally Caught Up with Transcription Factors

HotSpot Therapeutics recently announced a strategic collaboration with AbbVie to develop IRF5 transcription factor inhibitors for autoimmune diseases. The following…

by Geraldine Harriman
Read more
November 10, 2022

A Turning Point for Immuno-Oncology

Immunotherapy has been the holy grail in the fight against cancer for the last decade. For good reason, we’ve been...

by Tim Reilly
Read more
June 21, 2022

Hacking the Human Cell – How Once ‘Un-druggable’ Proteins Became the New Frontier in Drug Development

White Hat Hackers, sometimes called “ethical hackers,” are individuals that work to find and fix security problems in a system...

by Jonathan Montagu
Read more
Cat and machine learning
March 8, 2022

Staying Human in the Age of Artificial Intelligence

No, your next doctor will not be a robot. Nor will an algorithm cure cancer. However, AI technology will absolutely...

by Ramy Farid and Jonathan Montagu
Read more
Pieces of jigsaw puzzle and global network concept.
January 10, 2022

Making R&D ‘Smarter’ by Putting Artificial Intelligence into Practice

The pharmaceutical industry still faces unrelenting challenges across the entirety of the drug development landscape. According to Piper Sandler’s recent...

by Geraldine Harriman and Tim Reilly
Read more
November 29, 2021

Hitting the Spot

Today marks an important point in our journey to patients as HotSpot Therapeutics announces its $100MM Series C financing.  This infusion of…

by Jonathan Montagu
Read more
Wrecking ball destroying cancer cell
July 13, 2021

Immuno-Oncology: The Comeback Kid

Now 10 years into the golden era of immuno-oncology (I-O) following the first FDA approval of ipilimumab (anti-CTLA4) in 2011…

by Tim Reilly
Read more
DNA molecules on the beautiful backdrop
August 23, 2019

Hotspots meet DNA-encoded libraries

DNA encoded libraries (DEL) have received a lot of attention over the past few years. They’ve been hailed as “highly...

by Geraldine Harriman
Read more
July 31, 2019

Targeting the mTORC1 Pathway With Phenotypic Screening

The conventional approach to drug discovery shines a light on specific target proteins, using an arsenal of biochemical and virtual...

by Jonathan Montagu
Read more
Vector flat style illustration depicting biomedical research concept including handmade textures.
June 30, 2019

Biocentury Innovations shines a new light on allostery

I was excited to participate in Allison Johnson’s recent Biocentury article reflecting on the growing interest of industry in allostery and why...

by Geraldine Harriman
Read more