January 3, 2024

Signaling Complexes: A Ripe Opportunity for Drug Development

Signaling pathways are the intricate networks that govern cell behavior, lying at the crux of cell function. They are used...

by Jonathan Montagu
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June 1, 2023

How We Balance the What and How at HotSpot

At HotSpot, we are committed to building something we believe is truly distinctive, setting ourselves apart from our peers in...

by Jonathan Montagu
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April 28, 2023

Moving Our Core Values Beyond Table Stakes

Every company has a culture, either by design or default. From our inception in 2016, we wanted to create a...

by Jonathan Montagu
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March 1, 2023

Build It and They Will Come – New Review Spotlights the Scientific Momentum Building for CBL-B Inhibition

The phrase ‘build it and they will come’ dates all the way back to the Old Testament, and in more...

by Jonathan Montagu
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January 4, 2023

Reimagining I-O with Our First Investigational Drug and a New Approach to Clinical Discovery

HotSpot Therapeutics recently announced FDA clearance of our Investigational New Drug (IND) application for HST-1011, our small molecule allosteric inhibitor...

by Jonathan Montagu
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June 21, 2022

Hacking the Human Cell – How Once ‘Un-druggable’ Proteins Became the New Frontier in Drug Development

White Hat Hackers, sometimes called “ethical hackers,” are individuals that work to find and fix security problems in a system...

by Jonathan Montagu
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April 28, 2022

A Global Community

It is in moments like this that we are reminded of the collective power of good to overcome the disenfranchised…

by Jonathan Montagu
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November 29, 2021

Hitting the Spot

Today marks an important point in our journey to patients as HotSpot Therapeutics announces its $100MM Series C financing.  This infusion of…

by Jonathan Montagu
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April 15, 2021

Reimagining the Workplace Post Pandemic

Returning to work following the pandemic presents an opportunity to think creatively about how to re-configure the workplace

by Jonathan Montagu
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A flat vector image of scientists around a mikroscope
May 20, 2020

The Business of Science

Today marks an important milestone for HotSpot Therapeutics as we announce our Series B financing, but it also marks a...

by Jonathan Montagu
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